Scientific Publications

A critical role for Stat3 signaling in immune tolerance

Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

Combination therapy with AG-490 and interleukin 12 achieves greater antitumor effects than either agent alone

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest