Scientific Publications

Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis

Antiangiogenic and antimetastatic activity of JAK inhibitor AZD1480

Humanized Lewis-Y specific antibody based delivery of STAT3 siRNA

A requirement of STAT3 DNA binding precludes Th-1 immunostimulatory gene expression by NF-κB in tumors

STAT3 inhibition is a therapeutic strategy for ABC-like diffuse large B-cell lymphoma

The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival

STAT3: a target to enhance antitumor immune response

IL-17 enhances tumor development in carcinogen-induced skin cancer

STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors

Targeting STAT3 in adoptively transferred T cells promotes their in vivo expansion and antitumor effects

Targeting Stat3 in the myeloid compartment drastically improves the in vivo antitumor functions of adoptively transferred T cells

Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways